New Delhi, April 8 (IANS) A team of South Korean scientists has developed a new labelling technology that can observe neuronal structure in detail and help decode degenerative brain disorders like Alzheimer’s and Parkinson’s disease, as well as stroke — known to cause malfunction and progressive degeneration of the nerve cells.
The next-generation technology, named ‘NeuM’ (Neuronal Membrane-selective), enables successful monitoring of neuronal changes for up to 72 hours, said the team from the Korea Institute of Science and Technology (KIST).
NeuM works by “selectively labelling neuronal membranes, visualising neuronal structures, and allowing real-time monitoring of neuronal changes”.
The researchers explained that visualising neuronal changes is important both during the disease and in normal conditions.
This is because the structure and function of nerve cells continuously change while transmitting information from sensory organs to the brain.
While selectively labelling living neurons for real-time monitoring is imperative, current gene-based and antibody-based labelling technologies suffer from low accuracy and difficulty in long-term tracking.
NeuM, developed via the molecular design of neuronal cells, is likely to be a solution.
The technology comes with “excellent binding affinity to neuronal membranes, enabling long-term tracking and high-resolution imaging of neurons”, the researchers said.
“NeuM can distinguish ageing and degenerating neurons, becoming a crucial tool in elucidating the mechanisms of degenerative brain disorders and developing treatments,” said Dr. Kim Yun Kyung from the Brain Science Institute at KIST.
“In the future, we plan to refine NeuM for even more precise analysis of neurons by designing fluorescence wavelengths to distinguish colours such as green and red,” he added.
–IANS
rvt/rad
Disclaimer
The information contained in this website is for general information purposes only. The information is provided by TodayIndia.news and while we endeavour to keep the information up to date and correct, we make no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, suitability or availability with respect to the website or the information, products, services, or related graphics contained on the website for any purpose. Any reliance you place on such information is therefore strictly at your own risk.
In no event will we be liable for any loss or damage including without limitation, indirect or consequential loss or damage, or any loss or damage whatsoever arising from loss of data or profits arising out of, or in connection with, the use of this website.
Through this website you are able to link to other websites which are not under the control of TodayIndia.news We have no control over the nature, content and availability of those sites. The inclusion of any links does not necessarily imply a recommendation or endorse the views expressed within them.
Every effort is made to keep the website up and running smoothly. However, TodayIndia.news takes no responsibility for, and will not be liable for, the website being temporarily unavailable due to technical issues beyond our control.
For any legal details or query please visit original source link given with news or click on Go to Source.
Our translation service aims to offer the most accurate translation possible and we rarely experience any issues with news post. However, as the translation is carried out by third part tool there is a possibility for error to cause the occasional inaccuracy. We therefore require you to accept this disclaimer before confirming any translation news with us.
If you are not willing to accept this disclaimer then we recommend reading news post in its original language.
